NKT cells

Natural Killer T (NKT) cells are a heterogeneous group of T cells with some NK cells properties. Most clinical trials with NKT cells have been performed with CIK cells.

1. Recent Development in NKT-Based Immunotherapy of Glioblastoma: From Bench to Bedside
   Li Y, Sharma A, Maciaczyk J, Schmidt-Wolf IGH. Recent Development in NKT-Based Immunotherapy of Glioblastoma: From Bench to Bedside. Int J Mol Sci. 2022 Jan 24;23(3):1311. doi: 10.3390/ijms23031311. PMID: 35163235; PMCID: PMC8835986.

2. Natural killer T cells subsets in cancer, functional defects in prostate cancer and implications for immunotherapyNowak M, Schmidt-Wolf IG. Natural killer T cells subsets in cancer, functional defects in prostate cancer and implications for immunotherapy. Cancers (Basel). 2011 Sep 20;3(3):3661-75. doi: 10.3390/cancers3033661. PMID: 24212972; PMCID: PMC3759215.

3. Defective NKT cell activation by CD1d+ TRAMP prostate tumor cells is corrected by interleukin-12 with α-galactosylceramide
   Nowak M, Arredouani MS, Tun-Kyi A, Schmidt-Wolf I, Sanda MG, Balk SP, Exley MA. Defective NKT cell activation by CD1d+ TRAMP prostate tumor cells is corrected by interleukin-12 with α-galactosylceramide. PLoS One. 2010 Jun 25;5(6):e11311. doi: 10.1371/journal.pone.0011311. PMID: 20593019; PMCID: PMC2892484.

4. Propagation of large numbers of T cells with natural killer cell markers
   Schmidt-Wolf IG, Lefterova P, Johnston V, Huhn D, Blume KG, Negrin RS. Propagation of large numbers of T cells with natural killer cell markers. Br J Haematol. 1994 Jul;87(3):453-8. doi: 10.1111/j.1365-2141.1994.tb08297.x. PMID: 7527643.